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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR35
All Species:
33.64
Human Site:
S550
Identified Species:
67.27
UniProt:
Q9P2L0
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2L0
NP_001006658.1
1181
133547
S550
N
C
R
A
Y
Q
L
S
L
N
C
N
S
S
R
Chimpanzee
Pan troglodytes
XP_515315
1273
143538
S642
N
C
R
A
Y
Q
L
S
L
N
C
N
S
S
R
Rhesus Macaque
Macaca mulatta
XP_001107482
1296
146192
S665
N
C
R
G
Y
Q
L
S
L
N
C
N
S
S
R
Dog
Lupus familis
XP_532884
1356
153148
S550
N
C
R
A
Y
Q
L
S
L
N
C
N
S
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BND3
1181
133947
S550
D
C
R
A
C
Q
L
S
L
N
C
N
S
S
R
Rat
Rattus norvegicus
NP_001092810
1170
132761
S539
D
C
R
A
C
Q
L
S
L
N
C
N
S
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511461
679
76765
E115
Q
K
I
C
I
V
Y
E
D
G
A
V
I
V
G
Chicken
Gallus gallus
XP_419970
1197
135555
S569
N
C
R
A
H
Q
L
S
L
N
C
N
S
S
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001139061
1203
136070
S570
T
S
R
P
Y
Q
L
S
L
N
C
N
S
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647653
1205
135183
N557
I
A
N
V
A
L
R
N
R
H
L
M
N
A
K
Honey Bee
Apis mellifera
XP_394812
1185
134241
A555
I
N
C
D
S
S
R
A
A
I
M
D
L
S
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783217
1209
136043
S567
N
C
R
P
H
A
L
S
L
N
C
T
S
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.3
89.8
82
N.A.
92.2
91.7
N.A.
51.1
84.4
N.A.
78
N.A.
47.2
51.9
N.A.
66.3
Protein Similarity:
100
92.6
90.6
84.7
N.A.
96.7
96
N.A.
54.4
92.2
N.A.
88.4
N.A.
64.9
70.6
N.A.
80.5
P-Site Identity:
100
100
93.3
100
N.A.
86.6
86.6
N.A.
0
93.3
N.A.
80
N.A.
0
6.6
N.A.
73.3
P-Site Similarity:
100
100
93.3
100
N.A.
93.3
93.3
N.A.
0
100
N.A.
80
N.A.
33.3
20
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
50
9
9
0
9
9
0
9
0
0
9
0
% A
% Cys:
0
67
9
9
17
0
0
0
0
0
75
0
0
0
0
% C
% Asp:
17
0
0
9
0
0
0
0
9
0
0
9
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
0
0
0
0
0
9
0
0
0
0
17
% G
% His:
0
0
0
0
17
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
17
0
9
0
9
0
0
0
0
9
0
0
9
0
0
% I
% Lys:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
9
% K
% Leu:
0
0
0
0
0
9
75
0
75
0
9
0
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
0
% M
% Asn:
50
9
9
0
0
0
0
9
0
75
0
67
9
0
0
% N
% Pro:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
9
0
0
0
0
67
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
75
0
0
0
17
0
9
0
0
0
0
0
75
% R
% Ser:
0
9
0
0
9
9
0
75
0
0
0
0
75
84
0
% S
% Thr:
9
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% T
% Val:
0
0
0
9
0
9
0
0
0
0
0
9
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
42
0
9
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _